Zach Cregger has opened up about his approach to adapting Resident Evil in his new movie. Instead of a direct adaptation, the Weapons director is telling a new story set in the world of the franchise.

“I happen to worship these Resident Evil games and pull a lot of inspiration from the experience of playing them,” he said in a new featurette, before listing some of the references he included. “I tried to keep the environment changing every seven or eight minutes, like the games. You’re always moving into another level as it were.”

Cregger went on to explain that he includes weapon progression in the movie, from pistol to machine gun, as well as including healing spray cans, typewriters, and herbs. He’s even included a particularly niche frustration, which fans of the franchise will know all too well. “There’s a lot of items from the games, he’s constantly coming up against these padlocks that are stopping him from progressing,” he added.

As Cregger puts it, while the new movie won’t include Leon or adapt any particular story, “This is an opportunity for me to be loyal to the games in spirit and in tone and build a story that puts you in that scenario again and again, with increasing stakes.”

Resident Evil stars Austin Abrams as a hospital delivery driver tasked with taking an important package to Raccoon City hospital. However, what follows is no ordinary night as a viral outbreak of infected monsters swarm him as he makes the perilous journey.

The horror movie opens on September 18, 2026. For more scares, check out our guide to upcoming horror movies as well as a breakdown of all the new video game adaptations on the way in 2026 and beyond.